Your doctor may consider a number of ways to manage or treat OFF, dyskinesia or both.
This approach involves changing how much levodopa you take and how often you take it. Treatment strategies that adjust or limit levodopa therapies often result in a person with PD faced with a “trade-off”: either accept OFF or dyskinesia.
There are oral medications that may be used to treat OFF, dyskinesia or both.
Deep brain stimulation (DBS) or levodopa carbidopa gel implanted in the intestines may be considered, especially if medications cannot control symptoms well enough. For some people who have already had either of these surgical options but dyskinesia remains a problem, oral medications may also be an option (refer to “Oral medication” section).
Tips for making the most of your levodopa
- Drink a full glass of water with your medication. This allows the drug to fully dissolve and move through the digestive tract.
- Take your medication at least 30 minutes before or 1-2 hours after a meal.
- If you experience nausea, try a light low-protein snack, such as dry bread, soda crackers, or a piece of banana If the nausea does not resolve, call your doctor. You may need supplemental carbidopa to help resolve this side effect.4